Building Blocks Catalog

300 Thousand compounds in stock

Original and unique

Make-on-demand
Building Blocks

1B novel building blocks

Reliable supply

Custom Synthesis

Over 650 highly skillful chemists

Unique synthesis technologies

Library Synthesis

48B Billion REAL compounds and

Custom Library Synthesis

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On site access to all Enamine stock BB’s

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2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from February 2024

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  • 27 March 2024   Press Release

    Enamine Announces Expansion of Its Library Synthesis Capabilities

    March, 2024, Kyiv, Ukraine. Enamine Ltd, the global leader in supplying small molecules and early drug discovery services, announces the expansion of its library synthesis capabilities with a focus on Enamine REAL compounds to further support the growing demands of agricultural and pharmaceutical companies, research institutes, and drug discovery centers.

  • 01 March 2024   News

    Enamine and Genez International Announce Strategic Collaboration to Launch ...

    We are excited to announce a strategic collaboration between Enamine, the world's leading provider of chemical building blocks, compound libraries, and biology services, and Genez International, a prominent enterprise with 15 years of experience in cross-border supply management, biopharmaceutical research and development, semiconductor equipment, and high-definition digital imaging systems.

  • 21 February 2024   Press Release

    Cresset Announces Global Collaboration With Enamine on New Virtual ...

    Cresset recently announced a collaboration with Enamine, the world’s leading provider of chemical building blocks and drug discovery services to develop innovative new solutions for the early drug discovery process.

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Synthesis , 2012, 44 (08), 1263-1267

DOI: 10.1055/s-0031-1290808

Geraschenko O. V.; Khodakovskiy P. V.; Shivanyuk O. N.; Shishkin O. V.; Mykhailiuk P. K.; Tolmachev A. A.

Ethyl azol-2-ylglyoxylates react smoothly with acetone in the presence of catalytic amounts of proline and trifluoroacetic acid to give the corresponding azolyl aldols in 93-98% yield. The products are easily transformed into azolyl pyridazinones in 85-98% yield by cyclization with hydrazine hydrate.

Easy Synthesis of Novel 4-Azolylpyridazin-3-ones

Geraschenko O. V.; Khodakovskiy P. V.; Shivanyuk O. N.; Shishkin O. V.; Mykhailiuk P. K.; Tolmachev A. A.
Synthesis 2012, 44 (08), 1263-1267
DOI: 10.1055/s-0031-1290808

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