Monatsh. Chem. 2017, 148 (6), 1035-1041
DOI: 10.1007/s00706-016-1905-5
Yakovenko G.; Yagodkina M.; Bol’but A.; Shishkina S.; Vovk M. V.
Based on the tandem anionic cyclization of o-(azidomethyl)benzoates with 2-cyanoacetamides, an efficient synthetic route to the hitherto unknown heterocyclic system, triazolo[1,5-b][2,4]benzodiazepine, has been developed. The optimum reaction conditions have been found which provide 59–74% yields of target compounds. Their structural determination has been performed by the IR, LCMS, and NMR spectral methods as well as by X-ray diffraction analysis.