Synthesis , 2011, 07, 1149-1156
DOI: 10.1055/s-0030-1258448
Tolmachova N. A.; Dolovanyuk V. G.; Gerus I. I.; Kondratov I. S.; Polovinko V. V.; Bergander K.; Haufe G.
A series of 3-amino-6-(trifluoromethyl)-5,6-dihydropyridin-2(1H)-ones and 6-hydroxy-5,6-dihydropyridin-2(1H)-ones were hydrogenated to give the corresponding piperidinones. These lactams were used for the synthesis of novel trifluoromethyl-containing ornithine analogues and thalidomide mimetics.
Tolmachova N. A.; Dolovanyuk V. G.; Gerus I. I.; Kondratov I. S.; Polovinko V. V.; Bergander K.; Haufe G.
Synthesis 2011, 07, 1149-1156
DOI: 10.1055/s-0030-1258448