A One-Pot Fusion of Nitrogen-Containing Heterocycles

Aromatic and heteroaromatic dialkylaminoaldehydes react with various active methylene compounds in the presence of Me₃SiCl to give functionally and structurally diverse pyrrolo[1,2-a]quinolines, pyrido[1,2-a]quinolines, pyrazolo[3,4-e]indolizines, pyrazolo[4,3-c]quinolizines, benzo[g]pyrrolo[1,2-a]-1,8-naphthyridines, and benzo[g]pyrido[1,2-a]-1,8-naphthyridines in high yield and excellent purity.

Ryabukhin S. V.; Plaskon A. S.; Volochnyuk D. M.; Shivanyuk A. N.; Tolmachev A. A.
Synthesis 2007, 18, 2872-2886
DOI: 10.1055/s-2007-983842