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3-Functional substituted 4-trifluoromethyl tetrahydrothiophenes via [3 + 2]-cycloaddition reactions

J. Sulfur Chem. 2019, 40 (6), 629-640

DOI: 10.1080/17415993.2019.1633326

Markitanov Y.; Timoshenko V.; Rudenko T.; Rusanov E.; Shermolovich Y.

New 4-(trifluoromethyl)tetrahydrothiophenes containing an ester, sulfone, sulfoximine, sulfonamide, or phosphonate moiety at position 3 were synthesized by 1,3-dipolar [3 + 2]-cycloaddition reactions of 3,3,3-trifluoropropene derivatives and thiocarbonyl ylide generated in situ from chloromethyl trimethylsilylmethyl sulfide.

3-Functional substituted 4-trifluoromethyl tetrahydrothiophenes via [3 + 2]-cycloaddition reactions

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