News & Press Releases

Enamine Ltd., a leading compound supplier and BioSolveIT GmbH, a premium provider of drug discovery software, today announced the availability of the next generation of REAL Space Navigator, an efficient search tool within the world’s largest purchasable chemical space. Originally launched in February this year, Version 2 of REAL Space Navigator now offers ‘search and find’ access to an incredible 3.8 billion small molecular weight compounds ready for purchase.

Enamine and ChemAxon today announced the launch of jointly-created online resource (available at EnamineStore.com) to allow researchers worldwide to explore the chemical space of REAL database. The resource is aimed to provide the drug discovery community with the efficient solutions in hit-to-lead development. The querying of the chemical space is empowered by ChemAxon’s proprietary fast similarity search tool – MadFast, delivering sub-second response against hundreds of millions of molecules.

Enamine and BioSolveIT today announced the launch of the ‘REAL Space Navigator’. Jointly developed, the new software tool capitalizes on Enamine’s REAL (readily accessible) virtual compound concept and provides efficient ‘search & find’ access to more than 640 million pharma-oriented molecules, to date the world's largest chemical space of commercially accessible compounds.

Recent publication by our chemists describes gram-scale synthesis and some chemical transformations of novel trifunctional C₂ building blocks – MIDA boronate shown below.

Enamine Ltd. has today announced that it has expanded its collaboration on ZINC, a comprehensive online database of purchasable compounds curated by the Irwin and Shoichet laboratories in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF). Via ZINC, Enamine will provide researchers at UCSF and the global drug-discovery community with access to the company’s REAL database, a unique database of more than 300 million novel synthetically feasible chemical structures as an efficient source of potential new compounds for a breadth of drug discovery projects.

Diamond Light Source (Diamond) and the Structural Genomic Consortium (SGC) Oxford announced today that Enamine will become a key supplier of poised fragment and analogue libraries to its XChem facility. Enamine will offer a new generation of the hit-finding library, Diamond-SGC-iNEXT (DSI) Poised Library to enable fast and productive fragment-based lead discovery (FBLD).

Reactions conducted in autoclaves are very popular at Enamine because they allow synthesis of unique and novel building blocks that would not be doable otherwise. The key to their successful implementation into every day’s routine are quality pressure reactors that offer safe operations and are inexpensive at the same time.

Axxam S.p.A. and Enamine Ltd. announced the start of a Research Collaboration to enhance the Axxam small molecule screening library with the addition of a further set of compounds aimed at early-stage CNS drug discovery, achieving a total library size of ca. 280 000 compounds.

Enamine is organizing a research workshop within a framework of the company’s participation in a HORIZON-2020 project. The workshop will be held on June 17-19, 2017 in a hotel “Rus” under the supervision of Prof. I.V.Komarov.

Enamine Ltd. and the European Molecular Biology Laboratory (EMBL) have agreed to establish a collaboration whereby Enamine provides library synthesis, medicinal chemistry and biological services for the discovery and development of novel small molecules against EMBL’s proprietary anti-cancer targets.

Enamine is proud to announce that it has expanded its building blocks storage facility in Cincinnati totaling now 72 000 compounds. This allows Enamine to expedite logistics with its numerous US customers, offering a next-day delivery option for the majority of orders.

Enamine Ltd. has announced that it has agreed to expand its collaboration in early drug discovery with Actelion Pharmaceuticals, covering therapeutic areas including cardiovascular and central nervous system disorders, immunology, infectious diseases and oncology.

Enamine Ltd. and Danish biotech company Pcovery have announced that they have extended their collaboration for the discovery of new drugs for the treatment of invasive fungal infections and platform technology development.

EnamineStore expands its e-commerce functionality: online access to safety and analytical data on purchased compounds; requesting analogues; getting online quotes; automated order processing and more arrivals Read more...

Enamine is announcing the expansion of its building blocks storage in its Cincinnati, logistic center, reaching currently more than 50 000 novel substances, with the plan to reach through its continued efforts at least 60 000 building blocks until the end of 2016. The company fulfills in this way the request of its numerous USA customers to expedite delivery time and fasten projects start.

Enamine Ltd., a chemical company, producer of building blocks and screening libraries, announced today that it had signed a collaboration agreement with small molecule design house FCH Group Ltd (FCH).

Dr. Pavel MYKHAILIUK, CSO at Enamine, has become a finalist at European Young Chemist Award 2016. He gave a talk at 6th EuCheMS Chemistry Congress (Seville, Spain, September 11-15). The European Young Chemist Award 2016 is intended to showcase and recognise the excellent research being carried out by young scientists working in the chemical sciences.

This year Enamine celebrates 25 years of excellence in chemistry. In commemoration of this special event, we have launched a total discount program at EnamineStore.com. Please visit our online shop and apply for exceptional 25% discount for 160 000+ building blocks, 2 100 000+ screening compounds and 50 000+ fragments in stock.

Upon confirmation, your profile at EnamineStore will be granted with 25% discount that will be further automatically applied to all your online purchases made until October 31, 2016.

Hurry up! The program has just started today and the clock is ticking for this exclusive offer!

Enamine announces the launch of a mobile version of EnamineStore catalog of building blocks and screening compounds. Realizing the growing number of mobile internet users among our customers, we have developed EnamineStore Mobile^Beta which is optimized for smartphones and tablet PCs. We hope it will further improve catalog browsing and shopping experience for our customers and stimulate the use of new mobile technologies to access our website.

Please, read more at our blog and explore EnamineStore Mobile for yourself.

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Announced on 1^st March, 2016 ChemSpace, a global e-procurement marketplace for searching, purchasing and selling chemical building blocks, has already accumulated over 20 million unique reagents and become the world’s largest pool of purchasable building blocks for medicinal chemistry. ChemSpace’s powerful engine supports storage and operations with millions of chemical entries. The platform sets no limits for suppliers and thus provides access to the most actual information on innovative molecules that have just appeared on the market.