News & Press Releases

Recently Enamine has further improved the high-throughput synthesis workflow used for preparation of compounds offered through the REAL Database. Removal of production bottlenecks, application of optimized technological solutions and expansion of high performance preparative flash chromatography unit allowed us to shorten entire production cycle to 12-14 days. Currently we are able to produce up to 2,000 samples per month using this optimized procedure. 90% feasibility rate can be achieved after a single production cycle for typical compound sets. Compounds synthesized via the enhanced scheme can be delivered within 3 weeks after acceptance of an order.

EnamineStore at www.enaminestore.com was completely updated – both content and interface were affected by following changes:

• new products added to catalog: except for stock Screening Compounds and Building Blocks now it is possible to search, browse and order feasible screening compounds (REAL DB) and Tangible Building Blocks
• new search features: one-click 'Find Analogs' option, advanced search wizard, search by a list of CAS numbers and more
• tracking and current statuses for orders placed on-line
• supplemental data on stock compounds updated in catalog
• new look of catalog and cart pages, color coding for compounds in different categories

Molplex and Enamine announced a new partnership to offer Enamine's screening compounds through the Molplex on-line drug design and assay ready chemical supply services. The agreement is a major step towards eliminating the high start-up costs of drug discovery, bringing sophisticated drug design, compound management and assay ready chemistry to the world's drug discovery scientists on demand. The agreement adds Molplex online drug design systems to the deep experience in organic chemistry and compound management of Enamine to solve the problem of generating viable chemical leads for novel targets.

As from October 2010 Enamine provides access to NMR and LC/MS data for stock compounds through EnamineStore on-line service. Available spectral data for a compound of interest can be downloaded in PDF format by clicking the "Download spectral data" link located in the "Details" dialog accessible from the catalog section (search results). The analytical data can be accessed by registered users only.

Price of over 9 000 building blocks was reduced by 50% on average. Selected compounds were discounted by as much as 80%! The products affected by price reduction conform to high quality standards of Enamine and are available from stock. Over 1 500 building blocks from this set are also available for rush delivery in 1g batches. You can download the set of discounted building blocks as SDF, ISIS DB or PDF. Please visit EnamineStore to check current stock availability and order on-line.

Starting from January 2010, Enamine starts offering screening compounds via three separate libraries: Advanced, HTS and Historical collection. Advanced collection will always contain only novel and recently synthesized compounds, thus clients who persistently monitor additions to Enamine stock will spend less time and efforts to find new structural motifs. HTS collection will continue to be an indispensable source of compounds for various screening needs, providing unparalleled choice of diverse chemotypes. Historical collection will contain compounds representing scientific heritage of major regional research groups and institutions, particularly interesting for research programs in agro-chemistry and material science.