CAS 131880-16-5, Cat. No EN300-18527578
Reagent for trifluoromethylating
Umemoto reagent I is an electrophilic trifluoromethylating agent used to transfer the trifluoromethyl group to nucleophiles such as silyl enol ethers and β-ketoesters[1]. It is also employed in catalytic strategies including Pd-catalyzed aromatic C-H trifluoromethylation, Cu-catalyzed trifluoromethylation, and photoredox-catalyzed radical trifluoromethylation[2]. The reagent is a white crystalline solid that should be stored in a cool, dry place due to its potentially harmful properties.
Synonyms: S-(Trifluoromethyl)dibenzothiophenium tetrafluoroborate; Umemoto’s Reagent I
Selected publication
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Exploration of Fluorination Reagents Starting from FITS Reagents.
Umemoto T. J Fluor Chem 2014, 167, 3–15. DOI: 10.1016/j.jfluchem.2014.07.029
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S-(Trifluoromethyl)Dibenzothiophenium Tetrafluoroborate.
Riou M.; Koike T. Encyclopedia of Reagents for Organic Synthesis 2018, 1–3. DOI: 10.1002/047084289X.rn01212.pub2