Sterically hindered amines typically serve as more potent replacements of saturated nitrogen heterocycles, often increasing the solubility and metabolic stability of drug candidates. Furthermore, they form stable N-oxides thus enabling medicinal effects based on radical chemistry. Enamine chemists have assembled a noteworthy collection of sterically hindered amines for their use in screening and in fundamental research.
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Over 50 sterically hindered amines from stock on 5-10 gram scale.
