Primary Amines
Importance of carbon-nitrogen bond formation using primary amines made them an object of interest in organic synthesis and drug discovery. Enamine offers over 37 000 primary amines from stock ranging from small decorating building blocks to intermediates and complex scaffolds for library synthesis. Our collection is the largest in the world being continuously enriched with novel primary amines that we design and synthesize in our labs.
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Primary amines
Novel primary amines
Every month we synthesize hundreds of new primary amines that we immediately commercialize in our catalog available for browsing at EnamineStore. It is only with a delay sometimes of a few months that the new and in many cases unique items are published in the established aggregator platforms. If you are looking for original recently synthesized building blocks we encourage you to use our focused selection of 6 months.
Scaffolds
Our primary amines-based scaffolds are represented by a considerable number of building blocks with at least two variation points allowing selective chemical modification.
Building blocks for parallel synthesis
Primary amines have found a wide application in synthesis of compound libraries first of all because of smoothly running amide coupling, arylation, alkylation, reductive amination reactions etc. Using our in-house developed reactivity filters we have selected a range of primary amines that can provide clean reactions and high yields of the products. All compounds having side functionalities that interfere under majority of the reaction conditions have been removed from this set. Such set of primary amines can be easily shared on your request.
MADE primary amines
Having synthesized thousands of primary amines and having numerous starting materials in stock we can easily use our skills and documented knowledge to synthesize in short term analogous compounds to what we publish in our catalog. We have gathered our ideas of such new building blocks in a database that can be shared on request.
