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Primary amines

Importance of carbon-nitrogen bond formation using primary amines made them an object of interest in organic synthesis and drug discovery. Enamine offers over 27 000 primary amines from stock ranging from small decorating building blocks to intermediates and complex scaffolds for library synthesis. Our collection is the largest in the world being continuously enriched with novel primary amines that we design and synthesize in our labs.

Primary amines

 
Aliphatic
Aromatic
Bicyclic

Item

Original

Aliphatic


EN300-247581

Aromatic


EN300-245868

Bicyclic


EN300-42902

Item

Fluorinated

Aliphatic


EN300-213745

Aromatic


EN300-130149

Bicyclic


EN300-177922

Item

Bifunctional

Aliphatic


EN300-246766

Aromatic


EN300-122818

Bicyclic


EN300-88458

Novel primary amines

Every month we synthesize hundreds of new primary amines that we immediately commercialize in our catalogue available for browsing at EnamineStore. It is only with a delay sometimes of a few months that the new and in many cases unique items are published in the established aggregator platforms. If you are looking for original recently synthesized building blocks we encourage you to use our focused selection of 6 months.

Scaffolds

Our primary amines-based scaffolds are represented by a considerable number of building blocks with at least two variation points allowing selective chemical modification.

Building blocks for parallel synthesis

Primary amines have found a wide application in synthesis of compound libraries first of all because of smoothly running amide coupling, arylation, alkylation, reductive amination reactions etc. Using our in-house developed reactivity filters we have selected a range of primary amines that can provide clean reactions and high yields of the products. All compounds having side functionalities that interfere under majority of the reaction conditions have been removed from this set. Such set of primary amines can be easily shared on your request.


Special subsets

Fluorinated

N-monoprotected diamines

Amino acids and their derivatives

Bi- and polycyclic primary amines

REAL primary amines

Having synthesized thousands of primary amines and having numerous starting materials in stock we can easily use our skills and documented knowledge to synthesize in short term analogous compounds to what we publish in our catalogue. We have gathered our ideas of such new building blocks in a database that can be shared on request.

Services

Enamine offers world class service in chemical synthesis of a wide variety of organic compounds on the milligram to kilogram scale at competitive price.

Library Synthesis

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