Fluorinated Aliphatic Diazirines: Preparation, Characterization, and Model Photolabeling Studies
J. Org. Chem. 2023, 88 (1), 1-17
DOI: 10.1021/acs.joc.2c02262
Kornii Y.; Shablykin O.; Tarasiuk T.; Stepaniuk O.; Matvienko V.; Aloshyn D.; Zahorodniuk N.; Sadkova I.; Mykhailiuk P.
The previously unknown difluoromethyl diazirines and the previously neglected trifluoromethyl-aliphatic diazirines were synthesized and characterized. Model photolabeling experiments and biological studies showed that these compounds could indeed be used as photoaffinity labels.
