Incorporation of a sulfoximine group into bioactive compounds often improves their ADME/Tox profile, and enhances potency. Moreover, the moiety of sulfoximine is chemically and metabolically stable. NH-sulfoximines can serve as the both hydrogen bond donors and acceptors at the same time. Production and commercialization of the building blocks that already contain a sulfoximine group allow significant accelerating discovery of drug candidates. Herein we have designed and synthesized a library of sulfoximines for drug design.
Design
Unique properties:
-
↑ chemical stability;
↑ metabolic stability;
↑ aqueous solubility.
Download SD file
Download PDF file
We offer:
>100 unique sulfoximines on a 5-50 g scale from stock.
