A wide variety of fluoroaliphatic moieties remain severely underexplored in drug design, in contrast to the CF3-group, which is among the most frequently found fragments in modern pharmaceuticals. In recent years, a growing set of examples have demonstrated a considerable potential of variable non-traditional fluoroalkyl groups in both, medicinal chemistry and agrochemical fields. These structures may address the issues associated with lipophilicity profile and metabolic degradation schemes of biologically active molecules.
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More than 100 unique fluoroalkyl compounds from stock on a 5-10 g scale.
