Oxetane-incorporating Building Blocks

Increasing numbers of drug candidate molecules contain oxetane moieties, which are compact fragments with beneficial effects on the sp3 content and lipophilicity of molecules. Reagents for incorporating oxetanes into complex organic molecules are in high demand. Methyleneoxetanes are simple and versatile compounds that enable the construction of non-chiral oxetanes through standard as well as innovative organic reactions. Enamine scientists have prepared some of those reagents and even developed novel campaign=oxetane-incorporating-bbformations with them.

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Over 20 methyleneoxetanes from stock on 5-10 gram scale.


Methyleneoxetanes that are ready to be synthesized upon request.


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