Aliphatic γ-amino acids have served as core backbone elements of many drug structures. Introduction of cyclic elements and substituents enables restriction of the conformational landscape of the otherwise flexible γ-amino acid chains and changes physicochemical properties of the structures. Enamine offers a plethora of rare and unique γ-amino acid structures for modulating conformation, molecular volume, reactivity, and polarity.
Case study
We offer
Over 100 γ-amino acids from stock on 5-10 gram scale.