Epoxides for Drug Design

Epoxides are important heterocyclic units found in various naturally occurring molecules, some with potential bioactivities. At least fourteen drugs on the market are epoxide-containing. In addition, epoxides are valuable building blocks in medicinal chemistry. They react with nucleophiles in a ring-opening process to form new C-C, C-O and C-N bonds. Herein we have designed and synthesized a library of small heteroaliphatic epoxides for drug design.

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>100 unique epoxides on a 5-50 g scale from stock.


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