Incorporating anionic residues into peptides helps establish polar and charge-based interactions with target proteins, enhances the water solubility of peptide materials, and improves drug delivery. Chemical modifications of these anionic residues can further restrict the conformational landscape, strengthen interactions, and reduce metabolic degradation. Enamine offers a collection of anionic amino acids with diverse substituents, including innovative molecules built on cyclic scaffolds.
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More than 100 anionic amino acids from stock on 5-10 g scale.