3D-Shaped Scaffolds

Cyclic molecular skeletons are widely applied in the construction of medicinal molecules due to their ability to occupy binding pockets and impose conformational restrictions. Among these structures, symmetric forms like cubane and adamantane have been prevalent. In exploring their creative potential, Enamine chemists have prepared a panel of non-classical 3D-shaped cyclic scaffolds capable of occupying intermediate molecular volumes and lipophilicity values.

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Over 50 non-classical 3D-shaped compounds from stock on 5-10 gram scale.


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