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Alkyl halides are one of the most popular classes of functional compounds in medicinal chemistry. They are classical electrophilic reagents for the formation of C–N, C–O, C–S and C–C bonds through the corresponding alkylation reactions. Enamine offers over 10 000 alkyl halides from stock ranging from small decorating building blocks to intermediates and complex scaffolds for library synthesis. Our collection is the largest in the world being continuously enriched with novel alkyl halides that we design and synthesize in our labs.

Alkyl halides

 
Aliphatic
Heterocyclic
Small rings

Item

Original

Aliphatic


EN300-141727

Heterocyclic


EN300-103862

Small rings


EN300-302313

Item

Fluorinated

Aliphatic


EN300-309543

Heterocyclic


EN300-73180

Small rings


EN300-226423

Item

Bifunctional

Aliphatic


EN300-43754

Heterocyclic


EN300-83057

Small rings


EN300-188508

Novel alkyl halides

Every month we synthesize nearly a hundred new alkyl halides that we immediately commercialize in our catalog available for browsing at EnamineStore. It is only with a delay sometimes of a few months that the new and in many cases unique items are published in the established aggregator platforms. If you are looking for original recently synthesized building blocks we encourage you to use our focused selection of 6 months.

Building blocks for parallel synthesis

Alkyl halides have found a wide application in synthesis of compound libraries first of all because of smoothly running in various alkylation reactions. Using our in-house developed reactivity filters we have selected a range of alkyl halides that can provide clean reactions and high yields of the products. All compounds having side functionalities that interfere under majority of the reaction conditions have been removed from this set. Such set of alkyl halides can be easily shared on your request.

Special subsets

Fluorinated alkyl halides

Functionalized alkyl halides & linkers

Heterocyclic alkyl halides

MADE alkyl halides

Having synthesized thousands of alkyl halides and having numerous starting materials in stock we can easily use our skills and documented knowledge to synthesize in short term analogous compounds to what we publish in our catalog. We have gathered our ideas of such new building blocks in a database that can be shared on request.

Services

Enamine offers world class service in chemical synthesis of a wide variety of organic compounds on the milligram to kilogram scale at competitive price.

 

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