Alkyl halides are one of the most popular classes of functional compounds in medicinal chemistry. They are classical electrophilic reagents for the formation of C–N, C–O, C–S and C–C bonds through the corresponding alkylation reactions. Enamine offers over 10 000 alkyl halides from stock ranging from small decorating building blocks to intermediates and complex scaffolds for library synthesis. Our collection is the largest in the world being continuously enriched with novel alkyl halides that we design and synthesize in our labs.
Every month we synthesize nearly a hundred new alkyl halides that we immediately commercialize in our catalog available for browsing at EnamineStore. It is only with a delay sometimes of a few months that the new and in many cases unique items are published in the established aggregator platforms. If you are looking for original recently synthesized building blocks we encourage you to use our focused selection of 6 months.
Alkyl halides have found a wide application in synthesis of compound libraries first of all because of smoothly running in various alkylation reactions. Using our in-house developed reactivity filters we have selected a range of alkyl halides that can provide clean reactions and high yields of the products. All compounds having side functionalities that interfere under majority of the reaction conditions have been removed from this set. Such set of alkyl halides can be easily shared on your request.
Having synthesized thousands of alkyl halides and having numerous starting materials in stock we can easily use our skills and documented knowledge to synthesize in short term analogous compounds to what we publish in our catalog. We have gathered our ideas of such new building blocks in a database that can be shared on request.