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  • Synthesis of new polyhalogenoalkyl-containing phosphonates with an enaminone core and their use in the preparation of fluorinated heterocycles

Synthesis of Fluorinated Oxazoles by Oxidative Cyclization of Fluorinated Enamides

J. Fluorine Chem. 2017, 196, 88-97

DOI: 10.1016/j.jfluchem.2016.09.014

Shishlyk O.; Shcherbatiuk A.; Iminov R.; Tverdokhlebov A.; Tolmachev A.; Mykhailiuk P.; Biitseva A.
Novel approach to CF3-/CHF2-oxazoles was developed. The key reaction was oxidation of fluoroalkyl enamides with PhI(RCO2)2.

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