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Synthesis of Fluorinated Oxazoles by Oxidative Cyclization of Fluorinated Enamides

J. Fluorine Chem. 2017, 196, 88-97

DOI: 10.1016/j.jfluchem.2016.09.014

Shishlyk O.; Shcherbatiuk A.; Iminov R.; Tverdokhlebov A.; Tolmachev A.; Mykhailiuk P.; Biitseva A.
Novel approach to CF3-/CHF2-oxazoles was developed. The key reaction was oxidation of fluoroalkyl enamides with PhI(RCO2)2.

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