300 Thousand compounds in stock
Original and unique
Make-on-demand
Building Blocks
1B novel building blocks
Reliable supply
Over 650 highly skillful chemists
Unique synthesis technologies
48B Billion
REAL compounds and
Custom Library Synthesis
On site access to all Enamine stock BB’s
Highly flexible arrangements
2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from March 2024
Recent News
29 April 2024
Press Release
Kemptthal, Switzerland and Kyiv, Ukraine, April 29, 2024: Synple Chem, an innovative developer of integrated automated chemical synthesis solutions, announced today a strategic partnership with Enamine, a world-renowned supplier of building blocks. The partners agreed to jointly develop a new chemical space by fueling the world’s largest collection of building blocks provided by Enamine to Synple Chem’s reaction outcome prediction tools. Researchers will be able to download the resulting compound library and search it using their workflows. Selected compounds will be synthesized by Synple Chem’s automated synthesis platform.
11 April 2024
Press Release
Cambridge, UK and Kyiv, Ukraine, 11 April 2024: Metrion Biosciences Limited (“Metrion”), the specialist ion channel and cardiac safety screening contract research organisation (CRO) and drug discovery company, and Enamine Ltd (“Enamine”), the global leader in supplying small molecules and early drug discovery services, announced that Metrion has enhanced its High Throughput Screening (HTS) services with the addition of access to Enamine’s compound libraries.
27 March 2024
Press Release
March, 2024, Kyiv, Ukraine. Enamine Ltd, the global leader in supplying small molecules and early drug discovery services, announces the expansion of its library synthesis capabilities with a focus on Enamine REAL compounds to further support the growing demands of agricultural and pharmaceutical companies, research institutes, and drug discovery centers.
Drug Discovery Today
2019, 24 (2), 390-402
DOI:
10.1016/j.drudis.2018.10.016
Volochnyuk D.; Ryabukhin S.; Moroz Y; Savych O.; Chuprina A.; Horvath D.; Zabolotna Y.; Varnek A.; Judd D.
Over recent years, an industry of compound suppliers has grown to provide drug discovery with screening compounds: it is estimated that there are over 16 million compounds available from these sources. Here, we review the chemical space covered by suppliers’ compound libraries (SCL) in terms of compound physicochemical properties, novelty, diversity, and quality. We examine the feasibility of compiling high-quality vendor-based libraries avoiding complicated, expensive compound management activity, and compare the resulting libraries to the ChEMBL data set. We also consider how vendors have responded to the evolving requirements for drug discovery.
