Three-component synthesis of fluorinated pyrazoles from fluoroalkylamines, NaNO₂ and electron-deficient alkynes

Three-component reaction between RCF₂CH₂NH₂•HCl, NaNO₂ and electron-deficient alkynes significantly depends on substituent "R". The reaction gives the fluorinated pyrazoles in high yields when "R" is a fluorine atom or a fluoroalkyl group. With other "R" unexpected products are formed.