A Convenient Synthesis of (1H-Azol-1-yl)piperidines
Synthesis , 2012, 44 (13), 2041-2048
DOI: 10.1055/s-0031-1291126
Shevchuk N. V.; Liubchak K.; Nazarenko K. G.; Yurchenko A. A.; Volochnyuk D. M.; Grygorenko O. O.; Tolmachev A. A.
A convenient preparation of 3- and 4-(1H-azol-1-yl)piperidines by arylation of azoles (i.e., pyrazoles, imidazoles, and triazoles) with 3- and 4-bromopyridines and subsequent reduction of the pyridine ring was developed. The method was extended to benzo analogues of the title compounds.
Shevchuk N. V.; Liubchak K.; Nazarenko K. G.; Yurchenko A. A.; Volochnyuk D. M.; Grygorenko O. O.; Tolmachev A. A.
Synthesis 2012, 44 (13), 2041-2048
DOI: 10.1055/s-0031-1291126