Synthesis of functionalized bridged bicyclic sulfonamides with a bridgehead Nitrogen atom

Two approaches to synthesis of functionalized bridged bicyclic sulfonamides with a bridgehead Nitrogen atom were developed. The target compounds were obtained either by introduction of a CH₂SO₂ bridge into functionalized monocyclic substrates or by final‐step carboxylation of parent bicyclic cores. The described methods allowed preparation of the final products on a multigram scale.