One-Pot Synthesis of 6-Aminopyrido[2,3-d]pyrimidin-7-ones
Eur. J. Org. Chem. 2018, 46, 6519-6523
DOI: 10.1002/ejoc.201801204
Zinchenko A.; Muzychka L.; Kucher O.; Sadkova I.; Mykhailiuk P.; Smolii O.
One‐pot synthesis of 6‐aminopyrido[2,3‐d]pyrimidin‐7‐ones from 4‐aminopyrimidine‐5‐carbaldehydes and the in situ N‐protected methyl glycinate is developed. The obtained compounds have a polyfunctional character and provide opportunities for their use in drug design projects.
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