Synthesis of Functionalized Difluorocyclopropanes: Unique Building Blocks for Drug Discovery

Chem. Eur. J. , 2018, 24 (47)

DOI: 10.1002/chem.201705708

Bychek R.; Levterov V.; Sadkova I.; Tolmachev A. Mykhailiuk P.

Abstract Difluorocyclopropane‐containing building blocks for drug discovery were synthesized from the functionalized alkenes and TMSCF3/NaI. Novel fluorinated acids, amines, amino acids, alcohols, ketones and sulfonyl chlorides were obtained.


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