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Single Pharmacophore Fragments

Fragments for easy-to-analyse protein-ligand interaction

1 500 compounds

Recently, it was proposed that fragments with a single pharmacophore (i. e. polar group or other moiety for binding to a protein) have advantages over those with multiple, distally separated functional groups. This design approach is believed to maximize the advantages of FBDD, first of all through increasing synthetic capabilities of the fragment growth at the hit follow-up step. Applying these guidelines, we have created a library of single pharmacophore fragments.

Most popular Library Formats

Catalog ID
Compounds
Amount
Format
Price

Catalog ID

SPF-1500-10-Y-100

Compounds

1 500
5 plates

Amount

10 µL of 100 mM DMSO stock solutions

Plates and formats

384-well microplates, Echo qualified Labcyte, 320 compounds per plate

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Request a quote

Catalog ID

SPF-1500-25-Y-100

Compounds

1 500
5 plates

Amount

25 µL of 100 mM DMSO stock solutions

Plates and formats

384-well microplates, Echo qualified Labcyte, 320 compounds per plate

Request a quote

Request a quote

Catalog ID

SPF-1500-50-Y-100

Compounds

1 500
5 plates

Amount

50 µL of 100 mM DMSO stock solutions

Plates and formats

384-well microplates, Echo qualified Labcyte, 320 compounds per plate

Request a quote

Request a quote

Please request for any other options through our contact form. We will be happy to deliver our library in any convenient for your project formats.

Key features:

  • All the compounds pass both strict “ Ro2-like” physicochemical and most stringent in-house structural filters excluding PAINS, highly reactive and toxic motifs.
  • High variety of both pharmacophores and scaffolds bearing them
  • Rapid follow-up/fragment growth using both readily available in-stock and synthetic analogs from Enamine Fragments, Screening Collection and REAL Database

Examples of the molecules in the library

Molecular Properties

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