Dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate
CAS 2166-14-5, Cat. No EN300-211397
Versatile building block in Retro-Diels-Alder reactions
Dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate is a highly versatile heteroaromatic azadiene that has garnered considerable attention for its exceptional reactivity and its ability to engage in Retro-Diels-Alder reaction with a wide range of dienophiles and heterodienophiles. This compound is enabling the synthesis of substituted 1,2-diazines, 1,2,4-triazines, pyrroles, pyridines, indolines, and related condensed heterocycles through Cycloaddition Reactions that have an operationally simple procedure. Mildness of the reaction conditions and predictable positional selectivity, high level of functional group compatibility makes this heteroaromatic azadiene perfect as a reagent for pharmaceutically important targets.
Synonyms: 3,6-dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate