Reach out to new chemical space breaking the availability bias:
11 000 000 000 molecules and beyond

REAL compounds

The world’s largest collection of building blocks in stock:
169 144 and counting

New Building Blocks

Run HTS directly at Enamine or have your copy from
Ever-expanding collection of 3 million compounds

Screening Libraries & HTS

120 000 Fragment compounds
including 10 000 covalent binders


A broad test panel to support lead discovery
Integrated projects or a-la-carte service

ADME/T & in-vivo PK

Scientific research and development of techniques for the synthesis of organic compounds

High Fidelity Fragments

High Fidelity Library

Fragments of high MedChem tractability  

REAL Database

The largest enumerated database of synthetically feasible molecules

Functional Compounds

Impurity Reference Standards

Covalent Fragments

Covalent Fragments

Diverse covalent warheads with balanced reactivity

2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from May 2019

Recent News

  • 26 March 2019   Press Releases

    Enamine extends multi-year drug discovery collaboration with Lundbeck

    Enamine and H. Lundbeck A/S (Lundbeck) announced the expansion of their research collaboration. Enamine will support Lundbeck’s in-house discovery chemistry competencies with three principal assets enabling Lundbeck to optimally identify and develop hit series in its multiple research programs. A large diverse library of 100 000 new screening compounds was done for hit finding activities on numerous therapeutic targets. Enamine’s make-on-demand REAL compounds are for efficient access to billions of novel chemical compounds. Enamine FTE increased dedicated team of chemists to effectively support Lundbeck on all hit related follow-up activities backed by immediate access to over 170 000 building blocks in Enamine’s inventory.

    Read press release

  • 12 February 2019   News

    Enamine to Support Large-scale Hit Discovery Programs via New ...

    Scientists at the UCSF, together with colleagues at the UNC, created the largest “docking-friendly” database of molecules, based on the Readily Accessible (REAL) compounds from Enamine. Practical validation of the new database was recently published in Nature magazine, demonstrating that it is capable of identifying extremely powerful and synthetically available new hits.

  • 05 February 2019   News

    Horizon 2020 Project PELICO, Coordinated by Enamine, Achieves Promising ...

    EU-funded project PELICO, under Enamine’s coordination, reports promising results in synthesis of peptides, their pharmacokinetic and toxicity studies, and coupling with photo-controlled building blocks to yield new photo-controlled peptidomimetics.

Upcoming events

Enamine takes an active part in the industry’s life participating in the leading international conferences, symposiums, and other events. We will be happy to meet with you, exchange opinions on the latest developments and discuss current projects and future business opportunities. For more information please contact us at This email address is being protected from spambots. You need JavaScript enabled to view it.

2017 year

Date & Venue Event Presence
March 5 – 7
Vienna, Austria
Fragments 2017
6th RSC-BMCS Fragment-based Drug Discovery meeting


2016 year

Date & Venue Event Presence
November 30 – December 1
Lille, France 
Biofit 2016  Delegate 
November 28 – 29
Didcot, UK
Future of Fragments Symposium Sponsoring,
October 25 – 27
Berlin, Germany
12th Global Conference Intelligent Compound Libraries Sponsoring,
October 9 – 12
Boston, MA, USA
FBLD 2016
Fragment-based Lead Discovery Conference 2016
September 28 – 30
Autrans, France
École Thématique de Criblage 2016 Sponsoring
September 11 – 15
Seville, Spain
6th EuCheMS Chemistry Congress Delegate
August 31 –
September 3

Heidelberg, Germany
Chemical Biology 2016 Sponsoring
August 28 –
September 1

Manchester, UK
EFMC-ISMC 2016 Booth #11
August 7 – 12
Kyiv, Ukraine
18th European Symposium on Fluorine Chemistry Organiser
July 12 – 15
Melbourne, Australia 
2nd Fragment Based Drug Discovery Down Under Meeting
July 6 – 8
Caen, France
RICT: Interfacing Chemical Biology and Drug Discovery Booth #14
June 26 – 29
Chicago, Il, USA
National Medicinal Chemistry Symposium (NMCS) TBC
June 13 – 15
Verona, Italy
6th RSC / SCI symposium on GPCRs in Medicinal Chemistry TBC
June 2 – 3
Oxford, UK
Drug discovery: creating a new ecosystem Sponsoring 
May 16 – 17
Nottingham, UK
Kinase 2016: Next Generation Inhibitors Sponsoring,
May 10 – 11
Cambridge, UK
High Content & Phenotypic Screening 2016 (SelectBio) Sponsoring,
April 21
Hatfield, UK
27th symposium on Medicinal Chemistry in Eastern England Sponsoring
April 19 – 22
San Diego, USA
Drug Discovery Chemistry Booth
April 14
London, UK
RSC BMCS and RSC H&SG symposium: Synthesis in the Agrisciences Sponsoring
April 12 – 13
Berlin, German
Compound Management in Industry and Academia Conference #SLASCM16 Delegate
March 13 – 17
San Diego, USA
251st American Chemical Society National Meeting & Exposition (Computers in Chemistry) Booth,