Synthesis of Functionalized Difluorocyclopropanes: Unique Building Blocks for Drug Discovery
Chem. Eur. J. , 2018, 24 (47)
DOI: 10.1002/chem.201705708
Bychek R.; Levterov V.; Sadkova I.; Tolmachev A. Mykhailiuk P.
Abstract Difluorocyclopropane‐containing building blocks for drug discovery were synthesized from the functionalized alkenes and TMSCF3/NaI. Novel fluorinated acids, amines, amino acids, alcohols, ketones and sulfonyl chlorides were obtained.