CAS 1034-39-5, Cat. No EN300-1664590
Reagent for bromination
Triphenylphosphine dibromide is a reagent with many applications, primarily, converting alcohols, phenols, enols, ethers, and acetals into alkyl bromides or carboxylic acid derivatives into acyl bromides[1]. This method can be applied to sensitive substrates that contain cyclopropyl rings (e.g., cyclopropyl carbinol) or unsaturated compounds (e.g., cinnamyl alcohol and alkynediols) with minimal or no side reactions. Additionally, it facilitates the cyclization of amino alcohols to cyclic amines and can dehydrate and brominate carboxamide groups. The reagent is a moisture-sensitive, hygroscopic solid with corrosive properties that require careful handling.
Synonyms: bromotriphenylphosphonium bromide; dibromotriphenylphosphorane
Selected publication
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Triphenylphosphine Dibromide.
Dormoy J.; Castro B.; Bobinski T. Encyclopedia of Reagents for Organic Synthesis 2018, 1–13. DOI: 10.1002/047084289X.rt370.pub2