Hit Follow up Support
The success of a hit finding campaign heavily depends on quality of screening library and hit confirmation process. We offer seamless support in following-up the hits identified after screening of our Compound Libraries.
- Hit Confirmation: dry samples resupplied from the same batch, QC check, HPLC repurification, chiral resolution, impurities identification.
- Analogs: search within over 4.2M stock Screening Collection, REAL Database and REAL Space. Enumeration of new hit follow-up libraries.
- Resynthesis: typically within 3 weeks following in-house synthesis protocols.
If you purchase our screening library, you can fully benefit from our Compound Management services. We offer storage of the libraries in a special low-temperature facility and delivery of plate copies for screening or hit confirmation on your order.
Hit Confirmation
- Resupply from the same batch
- Quality control using advanced techniques
- HPLC purification, chiral separation
- Resynthesis and structure confirmation
Hit Expansion
- Analogs in Screening Collection, REAL Database and REAL Space
- Follow-up libraries design and enumeration of new molecules
- In silico screening services: Pharmacophore modeling and docking calculation, MD simulations.
Hit to Lead
- FTE-based Chemistry support
- Broad ADME panel
- PK studies
