More

Diels-Alder Reaction in the Synthesis of Fluorinated (Hetero)Aromatic Compounds

Eur. J. Org. Chem. 2018, (27-28)

DOI: 10.1002/ejoc.201800327

Kondratov I.; Tolmachova N.; Haufe G.

Numerous fluorinated (hetero)aromatic compounds have been synthesized by using the Diels–Alder reaction of fluorinated dienes/dienophiles with subsequent aromatization of the initially formed [4+2]‐cycloaddition products by various methods. This microreview presents diverse applications of the approach starting from the first examples in the 1960s up to recent advanced applications to illustrate the high potential of the method for the introduction of fluorine/polyfluoroalkyl substituents into (hetero)aromatic molecules.

Diels-Alder Reaction in the Synthesis of Fluorinated (Hetero)Aromatic Compounds

FOLLOW US

Contact us

Send a message