More

1-(Trimethylsilyl)vinyl MIDA Boronate: A Trifunctional C2 Building Block

Synthesis 2018, 50 (9), 1857-1861

DOI: 10.1055/s-0036-1591926

Ivon Y.; Voitenko Z.; Grygorenko O.

1-(Trimethylsilyl)vinyl MIDA boronate — a trifunctional C2 building block — is prepared in only two laboratory steps and 54% overall yield starting from readily available trimethyl(vinyl)silane. The title compound undergoes orthogonal functionalization at either of the groups present in its structure, for example, iodination at the trimethylsilyl moiety, epoxidation at the double bond, and Suzuki–Miyaura coupling at the MIDA boronate.

1-(Trimethylsilyl)vinyl MIDA Boronate: A Trifunctional C2 Building Block

FOLLOW US

Contact us

Send a message