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Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

Eur. J. Org. Chem. , 2014, 17, 3592-3598

DOI: 10.1002/ejoc.201402158

Artamonov O. S.; Slobodyanyuk E. Y.; Volochnyuk D. M.; Komarov I. V.; Tolmachev A. A.; Mykhailiuk P. K.

Five CF3-substituted 3-azabicyclo[n.1.0]alkanes were synthesized by CuCl-mediated trifluoromethylcyclopropanation reaction of the corresponding cyclic enamides with CF3CHN2.

Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

Artamonov O. S.; Slobodyanyuk E. Y.; Volochnyuk D. M.; Komarov I. V.; Tolmachev A. A.; Mykhailiuk P. K.
Eur. J. Org. Chem. 2014, 17, 3592-3598
DOI: 10.1002/ejoc.201402158

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