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11 April 2024
Press Release
Cambridge, UK and Kyiv, Ukraine, 11 April 2024: Metrion Biosciences Limited (“Metrion”), the specialist ion channel and cardiac safety screening contract research organisation (CRO) and drug discovery company, and Enamine Ltd (“Enamine”), the global leader in supplying small molecules and early drug discovery services, announced that Metrion has enhanced its High Throughput Screening (HTS) services with the addition of access to Enamine’s compound libraries.
27 March 2024
Press Release
March, 2024, Kyiv, Ukraine. Enamine Ltd, the global leader in supplying small molecules and early drug discovery services, announces the expansion of its library synthesis capabilities with a focus on Enamine REAL compounds to further support the growing demands of agricultural and pharmaceutical companies, research institutes, and drug discovery centers.
01 March 2024
News
We are excited to announce a strategic collaboration between Enamine, the world's leading provider of chemical building blocks, compound libraries, and biology services, and Genez International, a prominent enterprise with 15 years of experience in cross-border supply management, biopharmaceutical research and development, semiconductor equipment, and high-definition digital imaging systems.
New J. Chem.
2019, 43 (33), 13112-13121
DOI:
10.1039/c9nj01390c
Zhikol O.; Shishkina S.; Lipson V.; Semenenko A.; Mazepa A.; Borisov A.; Mateychenko P.
Three novel isomeric supramolecular dehydroepiandrosterone appended 1,2,3-triazole-based potential gelators were synthesized. Their ability to form gels in different solvents was studied experimentally as well as at the molecular level by means of molecular dynamics and quantum chemistry. The conformational changes and binding sites of the molecules were indicated and discussed. While the gelator molecule unfolding may be one of the prerequisites for gel formation, no straight correlation was found. We suggest two ways of gelation of the compounds under study. These ways result from the competition of the molecular entanglement and binding site interactions, depending strongly on the molecular spacer structure.
