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Novel spirocyclic and fused cyclopropane scaffolds for medicinal chemistry

Novel spirocyclic and fused cyclopropane scaffolds for medicinal chemistry

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Saturated Bioisosteres of Benzene with Improved Solubility

Saturated Bioisosteres of Benzene with Improved Solubility

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Cubanes for Drug Design

Cubanes for Drug Design

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CH-Activation of L-Proline analogues

CH-Activation of L-Proline analogues

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Application of AI to REALSpace: A Step Ahead to Expand the Synthetically Feasible Chemical Space

Application of AI to REALSpace: A Step Ahead to Expand the Synthetically Feasible Chemical Space

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Conformationally-rigid pyrrolidines with improved water solubility

Conformationally-rigid pyrrolidines with improved water solubility

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Aminosulfonyl fluorides for drug design

Aminosulfonyl fluorides for drug design

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Difluorocyclopropanes for drug discovery

Difluorocyclopropanes for drug discovery

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Novel spirocycles for drug discovery

Novel spirocycles for drug discovery

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Bicyclic amines for drug discovery by [2+2]-photocyclization

Bicyclic amines for drug discovery by [2+2]-photocyclization

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1,3-Oxazoles and 1,2,4-oxadiazoles as selective agonists of GPR40 receptor

1,3-Oxazoles and 1,2,4-oxadiazoles as selective agonists of GPR40 receptor

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Design and synthesis of novel 3D-shaped building blocks to “Escape the Flatland”

Design and synthesis of novel 3D-shaped building blocks to “Escape the Flatland”

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Proline analogues: advanced building blocks for drug design

Proline analogues: advanced building blocks for drug design

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New synthetic approach to diverse heterocyclic sulfonyl chlorides

New synthetic approach to diverse heterocyclic sulfonyl chlorides

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Conformationally restricted scaffolds by Double-Mannich reaction of cyclic ketones

Conformationally restricted scaffolds by Double-Mannich reaction of cyclic ketones

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Synthesis of unique pyrrolidines for drug discovery

Synthesis of unique pyrrolidines for drug discovery

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Design and synthesis of morpholine analogues

Design and synthesis of morpholine analogues

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Novel fluorinated amines for drug discovery

Novel fluorinated amines for drug discovery

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CF<sub>3</sub>CHN<sub>2</sub> and C<sub>2</sub>F<sub>5</sub>CHN<sub>2</sub>: highly underestimated reagents

CF3CHN2 and C2F5CHN2: highly underestimated reagents

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