Carboxylic Acid Fragment Library

Designed for specific protein targets and sensible onset

4 000 compounds

In response to high demand for new and small carboxylic acid we have created set of carefully selected specific molecules that strictly respond to FBDD requirements. Our carboxylic acid fragments are mainly consist from the compounds derived in the last three years from previously established at Enamine in-house program for design and producing diverse carboxylic acids to enlarge core Building Blocks Collection and diversification of decorating reagents.

Mainly this type of fragments has great potential for hit finding on new and difficult targets, e.g. protein-protein interaction, due to binding affinity to so called “hot-spot” residues. In addition there is probability of high solubility and good membrane permeability of discovered initial hit that often could be a limiting factor for phenotypic screening or in vivo activity of following investigation.

Typical Formats

Catalog No.
Compounds
Amount
Format
Price

Catalog No.

CAF-4-10-Y-100

Compounds

4 000
13 plates

Amount

10 µL of 100 mM solutions in DMSO

Plates and formats

384-well plates, Echo qualified Labcyte LP0200; 1, 2 and 23, 24 columns empty; 320 compounds per plate

Price

This email address is being protected from spambots. You need JavaScript enabled to view it.

Catalog No.

CAF-4-50-X-100

Compounds

4 000
50 plates

Amount

50 µL of 100 mM solutions in DMSO

Plates and formats

96-well plates, Greiner Cat. No 650201, 1 & 12 columns empty, 80 compounds per plate

Price

This email address is being protected from spambots. You need JavaScript enabled to view it.

Catalog No.

CAF-4-100-X-10

Compounds

4 000
50 plates

Amount

100 µL of 10 mM solutions in DMSO

Plates and formats

96-well plates, Greiner Cat. No 650201, round (U) bottom, 1 & 12 columns empty, 80 compounds per plate

Price

This email address is being protected from spambots. You need JavaScript enabled to view it.

Catalog No.

CAF-4

Compounds

4 000

Amount

Custom

Plates and formats

Any custom format

Price

This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Get more details

Download SD file

Carboxylic Acid Fragment Library

Library code: CAF-4

Version: 2 August 2023

4 000 compounds

Key features

  • High novelty and core diversity
  • Fast follow-up with stock available analogues & synthesis
  • Cherry-picking is available, customer preferred delivery format

Examples of the molecules in the library

FOLLOW US

Contact us

I have read and agree with Privacy Policy of Enamine

Send me details