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Carboxylic Acid Fragment Library

Designed for specific protein targets and sensible onset

4 000 compounds

In response to high demand for new and small carboxylic acid we have created set of carefully selected specific molecules that strictly respond to FBDD requirements. Our carboxylic acid fragments are mainly consist from the compounds derived in the last three years from previously established at Enamine in-house program for design and producing diverse carboxylic acids to enlarge core Building Blocks Collection and diversification of decorating reagents.

Mainly this type of fragments has great potential for hit finding on new and difficult targets, e.g. protein-protein interaction, due to binding affinity to so called “hot-spot” residues. In addition there is probability of high solubility and good membrane permeability of discovered initial hit that often could be a limiting factor for phenotypic screening or in vivo activity of following investigation.

Most popular library formats

Catalog No.
Compounds
Plates
Amount
Format
Price

Catalog No.

CAF-4-10-Y-100

Compounds

4 000

Plates

13

Amount

10 µL of 100 mM solutions in DMSO

Format

384-well plates, Eco qualified Labcyte LP0200; 1, 2 and 23, 24 columns empty; 320 compounds per plate

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Catalog No.

CAF-4-50-X-100

Compounds

4 000

Plates

50

Amount

50 µL of 100 mM solutions in DMSO

Format

96-well plates, Greiner Cat. No 650201, 1 & 12 columns empty, 80 compounds per plate

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Request a quote

Catalog No.

CAF-4-100-X-10

Compounds

4 000

Plates

50

Amount

100 µL of 10 mM solutions in DMSO

Format

96-well plates, Greiner Cat. No 650201, round (U) bottom, 80 compounds per plate, 1 & 12 columns empty

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Request a quote

Please request for any other options through our contact form. We will be happy to deliver our library in any convenient for your project formats.

Key features:

  • High novelty and core diversity
  • Fast follow-up with stock available analogues & synthesis
  • Cherry-picking is available, customer preferred delivery format

Examples of the molecules in the library

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