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Paper by Enamine chemists is featured on the JOC cover

JOC_cover_20200120

In a recent JOC paper, Enamine chemists reported a comprehensive study of regioselective [3 + 2] cycloaddition reactions – an efficient approach towards 3,5-disubstituted isoxazole building blocks bearing mono-, di- or trifluoromethyl substituents. More than 100 derivatives were obtained on up to 130 g scale, and multigram quantities of representative examples are available from EnamineStore at the isoxazole library.

A housane that our chemists built
Introducing alkyl substituent into the piperidine ...
 

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Thursday, 24 September 2020

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