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Building Block Catalogue

225 Thousand compounds in stock

Original and unique

Make-on-demand
Building Blocks

210 Million novel building blocks

Reliable supply

Custom Synthesis

Over 650 highly skillful chemists

Unique synthesis technologies

Library Synthesis

14 Billion REAL compounds and

Custom Library Synthesis

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On site access to all Enamine stock BB’s

Highly flexible arrangements

2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from July 2020

Recent News

  • 15 April 2020   Press Releases

    Enamine and Chemspace collaborate with Blue Dolphin Lead ...

    Today Enamine, a leading provider of small molecules and drug discovery services, Chemspace, an online catalog with the largest offer of small molecules to search and buy, and Blue Dolphin Lead Discovery, a research organization focused on a fee-for-service virtual screening, announced the launch of the collaboration to support drug discovery projects.

    Read press release

  • 30 March 2020   News

    Let’s fight COVID-19 together

    An international group of scientists from academia and industry, including Enamine, is trying to help combat COVID-19. This effort began when Chinese scientists worked rapidly to determine the structure of the novel SARS‑CoV‑2 main protease (Mpro), which triggered a massive crystal-based fragment screen at the XChem facility at UK’s Diamond Light Source. For more details, please visit https://www.diamond.ac.uk/covid-19. With the same urgency, the scientists are now trying to progress these data towards what is desperately needed: effective, easy-to-make anti-COVID drugs https://covid.postera.ai/covid.

  • 11 March 2020   Press Releases

    Enamine to be the exclusive supplier of Astex’ MiniFrag ...

    Enamine Ltd. and Astex Pharmaceuticals (UK) have cooperated to provide wide access to Astex’ MiniFrag library, an efficient Fragment-based Drug Discovery tool for identification of hot and warm spots of protein targets. The Library is readily available from Enamine in any suitable format, including dry samples or assay-ready high concentration (1M, 100mM) aqueous soaks in containers of preferred type. The detected MiniFrag hits can be followed-up with a wide range of stock available and synthetically feasible derivatives as well as with building blocks for introduction of the relevant structural features for lead optimization.

    Read press release

Upcoming events

Product catalog

Product name
Format/Size
Descriptions
Download file

Format/Size

6 120 compounds

Descriptions

Diverse covalent warheads with balanced reactivity

Download file

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Format/Size

3 200 compounds

Descriptions

The library of Cys-specific covalent electrophilic binders

Download file

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Format/Size

1 600 compounds

Descriptions

A unique set of 1 600 Lys specific binders

Download file

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Format/Size

1 800 compounds

Descriptions

Special selection of Serine focused irreversible binders

Download file

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Acrylamide Fragments Set

#ACR-2608

Format/Size

2 422 compounds

Descriptions

[descr-Covalent-Acrylamides-Set][/descr-Covalent-Acrylamides-Set]

Download file

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Boronic Fragments Set

#BF-860

Format/Size

1 859 compounds

Descriptions

Selection of boronic acids with pharmacophore bearing core

Download file

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Chloracetamide Fragments Set

#CLF-1623

Format/Size

1 623 compounds

Descriptions

Specially synthesized set of high-quality fragments

Download file

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Epoxides Fragment Set

#EPX-200-X

Format/Size

259 compounds

Descriptions

The attractive set of 200 diverse epoxides

Download file

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Sulfonyl fluoride Fragments Set

#SFF-582

Format/Size

1 085 compounds

Descriptions

A unique representation of diverse small sulfonyl fluorides

Download file

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Terminal acetylene Fragments Set

#TAC-2000

Format/Size

2 001 compounds

Descriptions

CH-active terminal acetylenes with most attractive structural cores

Download file

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Vinyl Sulfone Fragments Set

#VSF-471

Format/Size

471 compounds

Descriptions

The little library of vinyl sulfones with validated parallel synthesis protocols

Download file

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Services

Enamine offers world class service in chemical synthesis of a wide variety of organic compounds on the milligram to kilogram scale at competitive price.

Custom Synthesis

Library Synthesis

Support

We offer comprehensive support in developing your hit compounds. Naturally such programs are realised most efficiently when biological actives originate from our screening collection. However, even if the hit compounds are from the collections of other vendors lead identification and optimization projects can proceed most productively in our hands. Sometimes for this we only need to synthesize first examples of the given chemical series and validate synthesis route.

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