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Building Block Catalogue

225 Thousand compounds in stock

Original and unique

Make-on-demand
Building Blocks

210 Million novel building blocks

Reliable supply

Custom Synthesis

Over 650 highly skillful chemists

Unique synthesis technologies

Screening Libraries

2.7 Million compounds in stock

Fast delivery

Library Synthesis

14 Billion REAL compounds and

Custom Library Synthesis

FTE Chemistry Support

On site access to all Enamine stock BB’s

Highly flexible arrangements

MedChem Highlights

2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from September 2020

P(O)Me2-containing BBs
Aliphatic Trifluoroborates
Functionalized Vinyl Boronates
3D-shaped Spirocycles
Analogues of CF3-Pyridine
Sugar-like Building Blocks
Sulfoximines
gem-Difluorinated Amines
Cyclic Sulfonamides

Recent News

  • 24 September 2020   Press Releases

    Enamine is selected for Horizon 2020 global project “AIDD” ...

    Enamine Ltd., a leading chemical research organization and producer of the world’s largest collections of novel building blocks (225,000+) and screening compound libraries (2,740,000+), has joined the Advanced Machine Learning for Innovative Drug Discovery (AIDD) program, funded by the European Union within the framework of the Marie-Skłodowska-Curie Actions (MSCA) with a budget of Euros 3.93 million. The project, coordinated by Helmholtz Zentrum München,Germany, brings together fifteen institutions from eleven countries in addition to the University of British Columbia (Canada) to train sixteen PhD students in close collaboration with associated partners from the USA, Australia, China, Israel and other countries and develop next generation AI and Machine Learning (ML) models and systems for drug discovery.

    Read press release

  • 17 September 2020   Press Releases

    Enamine Ltd. Released Coronavirus Library to Support COVID-19 Research ...

    Enamine Ltd., a leading chemical research organization and producer of the world’s largest collections of novel building blocks (225,000+) and screening compound libraries (2,740,000+), today announced the release of the Coronavirus Library. The new screening library capitalizes on Enamine’s decades of chemical R&D, advanced library design expertise, and experience with creating focused antiviral libraries. Enamine is a participant of a global Open Science initiative “COVID Moonshot”, aimed at discovering novel therapeutics against SARS-CoV-2.

    Read press release

  • 15 April 2020   Press Releases

    Enamine and Chemspace collaborate with Blue Dolphin Lead ...

    Today Enamine, a leading provider of small molecules and drug discovery services, Chemspace, an online catalog with the largest offer of small molecules to search and buy, and Blue Dolphin Lead Discovery, a research organization focused on a fee-for-service virtual screening, announced the launch of the collaboration to support drug discovery projects.

    Read press release

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Product catalog

Product name
Format/Size
Descriptions
Download file

Covalent Fragments

Format/Size

6 120 compounds

Descriptions

Diverse covalent warheads with balanced reactivity

Download file

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Cysteine focused Covalent Fragments

#CYS-3840

Format/Size

3 200 compounds

Descriptions

The library of Cys-specific covalent electrophilic binders

Download file

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Lysine focused Covalent Fragments

#LYS-640-X

Format/Size

1 600 compounds

Descriptions

A unique set of 1 600 Lys specific binders

Download file

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Serine focused Covalent Fragments

#SER-800-X

Format/Size

1 800 compounds

Descriptions

Special selection of Serine focused irreversible binders

Download file

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Acrylamide Fragments Set

#ACR-2608

Format/Size

2 422 compounds

Descriptions

[descr-Covalent-Acrylamides-Set][/descr-Covalent-Acrylamides-Set]

Download file

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Boronic Fragments Set

#BF-860

Format/Size

1 859 compounds

Descriptions

Selection of boronic acids with pharmacophore bearing core

Download file

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Chloracetamide Fragments Set

#CLF-1623

Format/Size

1 623 compounds

Descriptions

Specially synthesized set of high-quality fragments

Download file

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Epoxides Fragment Set

#EPX-200-X

Format/Size

259 compounds

Descriptions

The attractive set of 200 diverse epoxides

Download file

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Sulfonyl fluoride Fragments Set

#SFF-582

Format/Size

1 085 compounds

Descriptions

A unique representation of diverse small sulfonyl fluorides

Download file

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Terminal acetylene Fragments Set

#TAC-2000

Format/Size

2 001 compounds

Descriptions

CH-active terminal acetylenes with most attractive structural cores

Download file

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Vinyl Sulfone Fragments Set

#VSF-471

Format/Size

471 compounds

Descriptions

The little library of vinyl sulfones with validated parallel synthesis protocols

Download file

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Services

Enamine offers world class service in chemical synthesis of a wide variety of organic compounds on the milligram to kilogram scale at competitive price.

Custom Synthesis

Library Synthesis

Support

We offer comprehensive support in developing your hit compounds. Naturally such programs are realised most efficiently when biological actives originate from our screening collection. However, even if the hit compounds are from the collections of other vendors lead identification and optimization projects can proceed most productively in our hands. Sometimes for this we only need to synthesize first examples of the given chemical series and validate synthesis route.

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