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Building Block Catalogue

240 Thousand compounds in stock

Original and unique

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Building Blocks

210 Million novel building blocks

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Custom Synthesis

Over 650 highly skillful chemists

Unique synthesis technologies

Screening Libraries

2.8 Million compounds in stock

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Library Synthesis

20 Billion REAL compounds and

Custom Library Synthesis

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On site access to all Enamine stock BB’s

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MedChem Highlights

2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from August 2021

Benzene mimics
SnAP Reagents
Bioisosteres of benzene
Diazirines
Heterocyclic scaffolds
Aliphatic Trifluoroborates
RSO2F
Cubanes
Sulfoximines
Cyclic Sulfonamides

Recent News

  • 09 September 2021   Press Releases

    OpenEye Scientific Partners with Enamine to Accelerate Early Drug ...

    SANTA FE, N.M., USA, & KYIV, Ukraine – September 9, 2021 – OpenEye Scientific and Enamine, a leading global provider of billions of new screening compounds to the drug discovery market, are partnering to enable faster and more accurate virtual screening of ultra-large compound libraries through access to innovative software.

    Read press release

  • 23 August 2021   News

    Drug design of covalent ligands with SeeSAR & Enamine ...

    We are proud to announce that our covalent compound library is now available in a ready-to-dock format for BioSolveIT’s drug design dashboard SeeSAR. Over 20 different warheads were processed and translated to their respective ligand-bound form to assess their binding mode after docking.

  • 24 June 2021   Press Releases

    Enamine selects Chemspace to advance its catalog business

    Kyiv, Ukraine, June 24, 2021. Enamine Ltd. a provider of drug discovery services empowered with the world’s largest collections of building blocks, fragments, and screening compounds announced today that it forms a strategic alliance with Chemspace, an online marketplace leader for small molecules, and will use the company as its exclusive aggregator platform to supply worldwide all its catalogue products starting from January 1, 2022. Chemspace will be the only online commercial resource in the world that will enable accessing and searching all Enamine’s catalogs. Enamine will continue direct supplies to the drug discovery community and at the same time will cease its historical collaborations with all other compound aggregator platforms.

    Read press release
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Product catalog

Product name
Format/Size
Descriptions
Download file

Covalent Fragments

Format/Size

6 120 compounds

Descriptions

Diverse covalent warheads with balanced reactivity

Download file

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Cysteine focused Covalent Fragments

#CYS-3840

Format/Size

3 200 compounds

Descriptions

Library of Cys-specific covalent electrophilic binders

Download file

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Lysine focused Covalent Fragments

#LYS-640-X

Format/Size

1 600 compounds

Descriptions

A unique set of 1 600 Lys specific binders

Download file

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Serine focused Covalent Fragments

#SER-800-X

Format/Size

1 800 compounds

Descriptions

Special selection of Serine focused irreversible binders

Download file

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Acrylamide Fragments Set

#ACR-2608

Format/Size

2 422 compounds

Descriptions

[descr-Covalent-Acrylamides-Set][/descr-Covalent-Acrylamides-Set]

Download file

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Boronic Fragments Set

#BF-860

Format/Size

1 859 compounds

Descriptions

Selection of boronic acids with pharmacophore bearing core

Download file

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Chloracetamide Fragments Set

#CLF-1623

Format/Size

1 623 compounds

Descriptions

Specially synthesized set of high-quality fragments

Download file

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Epoxides Fragment Set

#EPX-200-X

Format/Size

259 compounds

Descriptions

The attractive set of 200 diverse epoxides

Download file

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Sulfonyl fluoride Fragments Set

#SFF-582

Format/Size

1 085 compounds

Descriptions

A unique representation of diverse small sulfonyl fluorides

Download file

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Terminal acetylene Fragments Set

#TAC-2000

Format/Size

2 001 compounds

Descriptions

CH-active terminal acetylenes with most attractive structural cores

Download file

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Vinyl Sulfone Fragments Set

#VSF-471

Format/Size

471 compounds

Descriptions

The little library of vinyl sulfones with validated parallel synthesis protocols

Download file

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Services

Enamine offers world class service in chemical synthesis of a wide variety of organic compounds on the milligram to kilogram scale at competitive price.

Custom Synthesis

Library Synthesis

Support

We offer comprehensive support in developing your hit compounds. Naturally such programs are realised most efficiently when biological actives originate from our screening collection. However, even if the hit compounds are from the collections of other vendors lead identification and optimization projects can proceed most productively in our hands. Sometimes for this we only need to synthesize first examples of the given chemical series and validate synthesis route.

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