Building Blocks Catalog

300 Thousand compounds in stock

Original and unique

Make-on-demand
Building Blocks

1B novel building blocks

Reliable supply

Custom Synthesis

Over 650 highly skillful chemists

Unique synthesis technologies

Compound Libraries

Over 60 pre-plated libraries in stock

Fast delivery

Library Synthesis

48B Billion REAL compounds and

Custom Library Synthesis

FTE Chemistry Support

On site access to all Enamine stock BB’s

Highly flexible arrangements

MedChem Highlights

2 000 new building blocks are synthesized monthly. Here is an important update to our MedChem Highlights from March 2024

Heterocyclic scaffolds
gem-Difluorinated Amines
Morpholine Bioisosteres
Deuterium-containing BBs
Ideal Bioisostere
Piperidine Bioisostere
Piperazine Bioisosteres
7- and 8-Membered Rings
Cubanes

Recent News

  • 11 April 2024   Press Release

    Metrion Biosciences enhances High Throughput Screening services with access ...

    Cambridge, UK and Kyiv, Ukraine, 11 April 2024: Metrion Biosciences Limited (“Metrion”), the specialist ion channel and cardiac safety screening contract research organisation (CRO) and drug discovery company, and Enamine Ltd (“Enamine”), the global leader in supplying small molecules and early drug discovery services, announced that Metrion has enhanced its High Throughput Screening (HTS) services with the addition of access to Enamine’s compound libraries.

  • 27 March 2024   Press Release

    Enamine Announces Expansion of Its Library Synthesis Capabilities

    March, 2024, Kyiv, Ukraine. Enamine Ltd, the global leader in supplying small molecules and early drug discovery services, announces the expansion of its library synthesis capabilities with a focus on Enamine REAL compounds to further support the growing demands of agricultural and pharmaceutical companies, research institutes, and drug discovery centers.

  • 01 March 2024   News

    Enamine and Genez International Announce Strategic Collaboration to Launch ...

    We are excited to announce a strategic collaboration between Enamine, the world's leading provider of chemical building blocks, compound libraries, and biology services, and Genez International, a prominent enterprise with 15 years of experience in cross-border supply management, biopharmaceutical research and development, semiconductor equipment, and high-definition digital imaging systems.

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The full stock and virtual databases of Enamine’s compounds for the hit finding projects. Download, select, screen and follow-up.

Screening Collections

Stock collection containing over 4.2M compounds obtained internally using Enamine Building Blocks and in-house synthetic capabilities.

REAL Compounds

Most reliable ultra-large chemical database on the market for your virtual screening and synthesis with an average 80% success rate.

Fragments

Pre-selected compounds to be used in Fragment Based Drug Discovery and related fields.

Covalent Compounds

Covalent binders with most canonical as well as novel warheads.

Photoaffinity Compounds

For easy and efficient exploration of novel protein targets and proteomics screening platforms.

Bioactive Collection

Collection of FDA- approved drugs, “tool compounds” with validated biological activity, active metabolites/prodrugs and drug candidates.

PROTAC Toolbox (Protein degrader toolbox)

Stand-alone toolbox of active degraders, linkers, ligands and warheads from Enamine’s stock for purchase and design of new target molecules in the field of protein degradation.

Impurity Reference Standards

Rare and recently reported standards from stock. If not yet commercially available, we provide custom synthesis.

Macrocycles

Non-trivial compounds for screening and tackling “difficult” targets with extended binding sites and other unusual cases.

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